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EXPRESSION, PURIFICATION AND FUNCTIONAL RECONSTITUTION OF SLACK SODIUM-ACTIVATED POTASSIUM CHANNELS

The slack (slo2.2) gene codes for a potassium-channel alpha-subunit of the 6TM voltage-gated channel family. Expression of slack results in Na(+)-activated potassium channel activity in various cell types. In this paper we describe the purification and reconstitution of Slack protein, and show that...

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Main Authors: Yan, Yangyang, Yang, Youshan, Bian, Shumin, Sigworth, Fred J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903048/
https://ncbi.nlm.nih.gov/pubmed/22729647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-012-9425-7
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