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PKD1 intron 21: triplex DNA formation and effect on replication
Although autosomal dominant polycystic kidney disease is transmitted in an autosomal dominant fashion, there is evidence that the pathophysiology of cystogenesis involves a second hit somatic mutation superimposed upon the inherited germline mutation within the renal tubule cells. The polypurine·pol...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390299/ https://ncbi.nlm.nih.gov/pubmed/14990751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh312 |
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