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Next-generation sequencing reveals how RNA catalysts evolve from random space
Catalytic RNAs are attractive objects for studying molecular evolution. To understand how RNA libraries can evolve from randomness toward highly active catalysts, we analyze the original samples that led to the discovery of Diels–Alderase ribozymes by next-generation sequencing. Known structure-acti...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902939/ https://ncbi.nlm.nih.gov/pubmed/24157838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt949 |
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