Engineered reversal of drug resistance in cancer cells—metastases suppressor factors as change agents

Building molecular correlates of drug resistance in cancer and exploiting them for therapeutic intervention remains a pressing clinical need. To identify factors that impact drug resistance herein we built a model that couples inherent cell-based response toward drugs with transcriptomes of resistan...

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Dettagli Bibliografici
Autori principali: Yadav, Vinod Kumar, Kumar, Akinchan, Mann, Anita, Aggarwal, Suruchi, Kumar, Maneesh, Roy, Sumitabho Deb, Pore, Subrata Kumar, Banerjee, Rajkumar, Mahesh Kumar, Jerald, Thakur, Ram Krishna, Chowdhury, Shantanu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
Computational Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902936/
https://ncbi.nlm.nih.gov/pubmed/24157835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt946
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