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Mechanistic insights into the role of Hop2–Mnd1 in meiotic homologous DNA pairing
The Hop2–Mnd1 complex functions with the DMC1 recombinase in meiotic recombination. Hop2–Mnd1 stabilizes the DMC1-single-stranded DNA (ssDNA) filament and promotes the capture of the double-stranded DNA partner by the recombinase filament to assemble the synaptic complex. Herein, we define the actio...
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Main Authors: | , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Oxford University Press
2014
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902922/ https://ncbi.nlm.nih.gov/pubmed/24150939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt924 |
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