Mechanistic insights into the role of Hop2–Mnd1 in meiotic homologous DNA pairing

The Hop2–Mnd1 complex functions with the DMC1 recombinase in meiotic recombination. Hop2–Mnd1 stabilizes the DMC1-single-stranded DNA (ssDNA) filament and promotes the capture of the double-stranded DNA partner by the recombinase filament to assemble the synaptic complex. Herein, we define the actio...

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Autors principals: Zhao, Weixing, Saro, Dorina, Hammel, Michal, Kwon, YoungHo, Xu, Yuanyuan, Rambo, Robert P., Williams, Gareth J., Chi, Peter, Lu, Lucy, Pezza, Roberto J., Camerini-Otero, R. Daniel, Tainer, John A., Wang, Hong-Wei, Sung, Patrick
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902922/
https://ncbi.nlm.nih.gov/pubmed/24150939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt924
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