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Intrinsically disordered regions of nucleophosmin/B23 regulate its RNA binding activity through their inter- and intra-molecular association

Nucleophosmin (NPM1/B23) is a nucleolar protein implicated in growth-associated functions, in which the RNA binding activity of B23 plays essential roles in ribosome biogenesis. The C-terminal globular domain (CTD) of B23 has been believed to be the RNA binding domain because the splicing variant B2...

詳細記述

保存先:
書誌詳細
主要な著者: Hisaoka, Miharu, Nagata, Kyosuke, Okuwaki, Mitsuru
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
RNA
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902904/
https://ncbi.nlm.nih.gov/pubmed/24106084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt897
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