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The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart

The Polycomb-group protein, Ezh2, is required for epigenetic gene silencing in the adult heart by unknown mechanism. We investigated the role of Ezh2 and non-coding RNAs in a mouse model of pressure overload using transverse aortic constriction (TAC) attenuated by the prototypical histone deacetylas...

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Hlavní autoři: Mathiyalagan, Prabhu, Okabe, Jun, Chang, Lisa, Su, Yidan, Du, Xiao-Jun, El-Osta, Assam
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902903/
https://ncbi.nlm.nih.gov/pubmed/24137001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt896
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