Adipose-Derived Mesenchymal Stromal Cells From Aged Patients With Coronary Artery Disease Keep Mesenchymal Stromal Cell Properties but Exhibit Characteristics of Aging and Have Impaired Angiogenic Potential

Tissue regeneration is impaired in aged individuals. Adipose-derived mesenchymal stromal cells (ADSCs), a promising source for cell therapy, were shown to secrete various angiogenic factors and improve vascularization of ischemic tissues. We analyzed how patient age affected the angiogenic propertie...

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Bibliographic Details
Main Authors: Efimenko, Anastasia, Dzhoyashvili, Nina, Kalinina, Natalia, Kochegura, Tatiana, Akchurin, Renat, Tkachuk, Vsevolod, Parfyonova, Yelena
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2014
Subjects:
Tissue-Specific Progenitor and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902283/
https://ncbi.nlm.nih.gov/pubmed/24353175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0014
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