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Hijacking T cell differentiation: New insights in TLX function in T-ALL

TLX1 and TLX3 are two closely related homeobox transcriptional repressors frequently misexpressed and translocated in T cell acute lymphoblastic leukemia (T-ALL). In this issue of Cancer Cell, Dadi et al. provide new insights into how these factors are recruited by ETS-1 to the TCRα enhancer and act...

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Autors principals: King, Bryan, Ntziachristos, Panagiotis, Aifantis, Iannis
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902167/
https://ncbi.nlm.nih.gov/pubmed/22516255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.03.026
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