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Inhibitors of HIV-1 replication that inhibit HIV integrase.

HIV-1 replication depends on the viral enzyme integrase that mediates integration of a DNA copy of the virus into the host cell genome. This enzyme represents a novel target to which antiviral agents might be directed. Three compounds, 3,5-dicaffeoylquinic acid, 1-methoxyoxalyl-3,5-dicaffeoylquinic...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Robinson, W E, Reinecke, M G, Abdel-Malek, S, Jia, Q, Chow, S A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39021/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692814/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6326
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