Tryptophan biosynthesis protects mycobacteria from CD4 T cell-mediated killing

Bacteria that cause disease rely on their ability to counteract and overcome host defenses. Here we present a genome-scale study of Mycobacterium tuberculosis (Mtb) that uncovers the bacterial determinants of surviving host immunity, sets of genes we term “counteractomes.” Through this, we find that...

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Detalhes bibliográficos
Main Authors: Zhang, Yanjia J., Reddy, Manchi C., Ioerger, Thomas R., Rothchild, Alissa C., Dartois, Veronique, Schuster, Brian M., Trauner, Andrej, Wallis, Deeann, Galaviz, Stacy, Huttenhower, Curtis, Sacchettini, James C., Behar, Samuel M., Rubin, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902092/
https://ncbi.nlm.nih.gov/pubmed/24315099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.045
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