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Thymine Photodimer Formation in DNA Hairpins. Unusual Conformations Favor (6-4) vs. (2+2) Adducts

The photochemical reactions of eleven synthetic DNA hairpins possessing a single TT step either in a base-paired stem or in a hexanucleotide linker have been investigated. The major reaction products have been identified as the cis-syn (2+2) adduct and the (6-4) adduct on the basis of their spectros...

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Detalhes bibliográficos
Main Authors: Hariharan, Mahesh, Siegmund, Karsten, Saurel, Clifton, McCullagh, Martin, Schatz, George C., Lewis, Frederick D
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902035/
https://ncbi.nlm.nih.gov/pubmed/24212351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3pp50283j
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