Dysregulated Alternative Splicing Pattern of PKCδ during Differentiation of Human Preadipocytes Represents Distinct Differences between Lean and Obese Adipocytes

Obesity and its comorbidities affect millions of people. Here, we demonstrate that human preadipocytes are susceptible to programmed cell death (apoptosis) while mature adipocytes are resistant to apoptosis. The molecular mechanisms underlying the phenotype of apoptosis-resistant adipocytes are less...

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Hlavní autoři: Carter, Gay, Apostolatos, André, Patel, Rekha, Mathur, Abhishek, Cooper, Denise, Murr, Michel, Patel, Niketa A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901959/
https://ncbi.nlm.nih.gov/pubmed/24533217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/161345
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