Dysregulated Alternative Splicing Pattern of PKCδ during Differentiation of Human Preadipocytes Represents Distinct Differences between Lean and Obese Adipocytes

Obesity and its comorbidities affect millions of people. Here, we demonstrate that human preadipocytes are susceptible to programmed cell death (apoptosis) while mature adipocytes are resistant to apoptosis. The molecular mechanisms underlying the phenotype of apoptosis-resistant adipocytes are less...

詳細記述

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書誌詳細
主要な著者: Carter, Gay, Apostolatos, André, Patel, Rekha, Mathur, Abhishek, Cooper, Denise, Murr, Michel, Patel, Niketa A.
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901959/
https://ncbi.nlm.nih.gov/pubmed/24533217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/161345
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