Molecular cloning and characterization of hepatitis A virus cDNA.

Double-stranded cDNA was synthesized from hepatitis A virus (HAV) RNA and inserted into the Pst I site of pBR322. Restriction endonuclease digestion and cross-hybridization of fragments yielded a map of overlapping cloned cDNAs that included at least 99% of the viral genome. Molecular clones contain...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ticehurst, J R, Racaniello, V R, Baroudy, B M, Baltimore, D, Purcell, R H, Feinstone, S M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390180/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6310601/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.19.5885
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