Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.

The conformationally restricted, cyclic, disulfide-containing, enkephalin analogs [2-D-penicillamine, 5-L-penicillamine]enkephalin [(D-Pen2,L-Pen5]enkephalin) and [2-D-penicillamine, 5-D-penicillamine]enkephalin [(D-Pen2,D-Pen5]enkephalin) were synthesized by solid-phase methods. Selectivities of th...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Mosberg, H I, Hurst, R, Hruby, V J, Gee, K, Yamamura, H I, Galligan, J J, Burks, T F
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1983
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6310598/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.19.5871
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