Glutamine methylation in Histone H2A is an RNA Polymerase I dedicated modification

Nucleosomes are decorated with numerous post-translational modifications capable of influencing many DNA processes(1). Here, we describe a new class of histone modification, methylation of glutamine, occurring on yeast histone H2A at position 105 (Q105) and human H2A at Q104. We identify Nop1 as the...

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Bibliographic Details
Main Authors: Tessarz, Peter, Santos-Rosa, Helena, Robson, Sam C., Sylvestersen, Kathrine B., Nelson, Christopher J, Nielsen, Michael L., Kouzarides, Tony
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901671/
https://ncbi.nlm.nih.gov/pubmed/24352239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12819
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