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Blunted accumbal dopamine response to cocaine following chronic social stress in female rats: exploring a link between depression and drug abuse

RATIONALE: Women have twice the risk as men to develop depression. Approximately, 24% of major depression disorder cases have comorbid disorders with substance abuse. Several central systems, including dopaminergic and serotonergic pathways, are thought to be involved in such comorbidity. OBJECTIVES...

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Main Authors: Shimamoto, Akiko, DeBold, Joseph F., Holly, Elizabeth N., Miczek, Klaus A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901580/
https://ncbi.nlm.nih.gov/pubmed/21638221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2364-7
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