Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy

[Image: see text] The self-assembly of normally soluble proteins into fibrillar amyloid structures is associated with a range of neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases. In the present study, we show that specific events in the kinetics of the complex, multistep agg...

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Autores principales: Pinotsi, Dorothea, Buell, Alexander K., Galvagnion, Celine, Dobson, Christopher M., Kaminski Schierle, Gabriele S., Kaminski, Clemens F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2013
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901574/
https://ncbi.nlm.nih.gov/pubmed/24303845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl4041093
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