Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug

Immuno-isolation of islets has the potential to enable the replacement of pancreatic function in diabetic patients. However, host response to the encapsulated islets frequently leads to fibrotic overgrowth with subsequent impairment of the transplanted grafts. Here, we identified and incorporated an...

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Main Authors: Dang, Tram T., Thai, Anh V., Cohen, Joshua, Slosberg, Jeremy E., Siniakowicz, Karolina, Doloff, Joshua C., Ma, Minglin, Hollister-Lock, Jennifer, Tang, Katherine, Gu, Zhen, Cheng, Hao, Weir, Gordon C., Langer, Robert, Anderson, Daniel G.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901568/
https://ncbi.nlm.nih.gov/pubmed/23660251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.04.016
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