NT-3 Replacement with Brain-Derived Neurotrophic Factor Redirects Vestibular Nerve Fibers to the Cochlea

Survival of inner ear sensory neurons depends on two neurotrophins, BDNF and NT-3, and their respective receptors, TrkB and TrkC. Because both receptors are present in the same neuron, it has been suggested that BDNF and NT-3 are functionally redundant in promoting neuronal survival. Knock-in of one...

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Bibliographic Details
Main Authors: Tessarollo, Lino, Coppola, Vincenzo, Fritzsch, Bernd
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Development/Plasticity/Repair
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901528/
https://ncbi.nlm.nih.gov/pubmed/15014133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5514-03.2004
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