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Conditional and inducible gene recombineering in the mouse inner ear

Genetically engineered mice have greatly improved our understanding of gene functions and disease mechanisms. Nevertheless, the traditional knock-out approach has limitations in the overall viability of mutants. The application of the Cre/loxP system in the inner ear can help bypass this difficulty...

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Detalhes bibliográficos
Main Authors: Tian, Yong, James, Sally, Zuo, Jian, Fritzsch, Bernd, Beisel, Kirk W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901521/
https://ncbi.nlm.nih.gov/pubmed/16488403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2006.01.040
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