Measuring Protein-Ligand Interactions Using Liquid Sample Desorption Electrospray Ionization Mass Spectrometry

We have shown previously that liquid sample desorption electrospray ionization-mass spectrometry (DESI-MS) is able to measure large proteins and noncovalently-bound protein complexes (to 150 kDa) (Ferguson et al., Anal. Chem. 2011, 83, 6468-6473). In this study, we further investigate the applicatio...

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Main Authors: Liu, Pengyuan, Zhang, Jiang, Ferguson, Carly N., Chen, Hao, Loo, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901310/
https://ncbi.nlm.nih.gov/pubmed/24237005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac402906d
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