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Prothrombin is activated on vascular endothelial cells by factor Xa and calcium.

Vascular endothelial cells derived from adult bovine aorta (ABAE) treated with factor Xa and calcium were found to activate prothrombin. In contrast, nonvascular cells (human foreskin fibroblasts, bovine corneal endothelial cells, or human fetal lung cells) had either no or very little effect on pro...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Rodgers, G M, Shuman, M A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6580622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.22.7001
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