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Glucocorticoids regulate proopiomelanocortin gene expression in vivo at the levels of transcription and secretion.

After adrenalectomy, the plasma levels of adrenocorticotropic hormone (corticotropin, ACTH)/endorphin peptides in rats rise dramatically in the first 4 hr while pituitary peptide levels fall sharply. Eight hours after adrenalectomy, plasma levels are near control values again but they then increase...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Birnberg, N C, Lissitzky, J C, Hinman, M, Herbert, E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390110/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316340/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.22.6982
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