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Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid.

A pigeon cytochrome c-specific and Ia molecule-restricted T-cell hybrid was used as an immunogen in order to obtain monoclonal anti-antigen receptor antibodies. Two antibodies were isolated that specifically bound to and inhibited interleukin (IL) 2 release from only the immunizing clone. Lectin-ind...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Samelson, L E, Germain, R N, Schwartz, R H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390108/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316339/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.22.6972
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