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Evolutionary implications of a third lymphocyte lineage in lampreys

Jawed vertebrates (gnathostomes) and jawless vertebrates (cyclostomes) have different adaptive immune systems(1,2). Gnathostomes use T- and B-cell antigen receptors belonging to the immunoglobulin superfamily(3,4). Cyclostomes, the lampreys and hagfish, instead use leucine-rich repeat proteins to co...

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Detalhes bibliográficos
Main Authors: Hirano, Masayuki, Guo, Peng, McCurley, Nathanael, Schorpp, Michael, Das, Sabyasachi, Boehm, Thomas, Cooper, Max D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901013/
https://ncbi.nlm.nih.gov/pubmed/23934109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12467
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