Glucose-stimulated Single Pancreatic Islets Sustain Increased Cytosolic ATP Levels during Initial Ca(2+) Influx and Subsequent Ca(2+) Oscillations

In pancreatic islets, insulin secretion occurs via synchronous elevation of Ca(2+) levels throughout the islets during high glucose conditions. This Ca(2+) elevation has two phases: a quick increase, observed after the glucose stimulus, followed by prolonged oscillations. In these processes, the ele...

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Detalhes bibliográficos
Main Authors: Tanaka, Takashi, Nagashima, Kazuaki, Inagaki, Nobuya, Kioka, Hidetaka, Takashima, Seiji, Fukuoka, Hajime, Noji, Hiroyuki, Kakizuka, Akira, Imamura, Hiromi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900966/
https://ncbi.nlm.nih.gov/pubmed/24302735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.499111
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