Down-regulation of Mortalin Exacerbates Aβ-mediated Mitochondrial Fragmentation and Dysfunction

Mitochondrial dynamics greatly influence the biogenesis and morphology of mitochondria. Mitochondria are particularly important in neurons, which have a high demand for energy. Therefore, mitochondrial dysfunction is strongly associated with neurodegenerative diseases. Until now various post-transla...

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Hlavní autoři: Park, So Jung, Shin, Ji Hyun, Jeong, Jae In, Song, Ji Hoon, Jo, Yoon Kyung, Kim, Eun Sung, Lee, Eunjoo H., Hwang, Jung Jin, Lee, Eun Kyung, Chung, Sun Ju, Koh, Jae-Young, Jo, Dong-Gyu, Cho, Dong-Hyung
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Neurobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900965/
https://ncbi.nlm.nih.gov/pubmed/24324263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.492587
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