MicroRNAs Contribute to Induced Pluripotent Stem Cell Somatic Donor Memory

Induced pluripotent stem cells (iPSCs) maintain during the first few culture passages a set of epigenetic marks and metabolites characteristic of their somatic cell of origin, a concept defined as epigenetic donor memory. These residual somatic features are lost over time after extensive culture pas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vitaloni, Marianna, Pulecio, Julian, Bilic, Josipa, Kuebler, Bernd, Laricchia-Robbio, Leopoldo, Izpisua Belmonte, Juan Carlos
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900956/
https://ncbi.nlm.nih.gov/pubmed/24311783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.538702
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