Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase

The ankyrin and SOCS (suppressor of cytokine signaling) box (ASB) family of proteins function as the substrate recognition subunit in a subset of Elongin-Cullin-SOCS (ECS) E3 ubiquitin ligases. Despite counting 18 members in humans, the identity of the physiological targets of the Asb proteins remai...

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Autores principales: Andresen, Christina Aaen, Smedegaard, Stine, Sylvestersen, Kathrine Beck, Svensson, Charlotte, Iglesias-Gato, Diego, Cazzamali, Giuseppe, Nielsen, Tine Kragh, Nielsen, Michael Lund, Flores-Morales, Amilcar
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900953/
https://ncbi.nlm.nih.gov/pubmed/24337577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534602
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