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CYP82Y1 Is N-Methylcanadine 1-Hydroxylase, a Key Noscapine Biosynthetic Enzyme in Opium Poppy

Noscapine is a phthalideisoquinoline alkaloid investigated for its potent pharmacological properties. Although structurally elucidated more than a century ago, the biosynthesis of noscapine has not been established. Radiotracer studies have shown that noscapine is derived from the protoberberine alk...

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Bibliografische gegevens
Hoofdauteurs: Dang, Thu-Thuy T., Facchini, Peter J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900951/
https://ncbi.nlm.nih.gov/pubmed/24324259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505099
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