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The Antidepressant 5-HT(2A) Receptor Antagonists Pizotifen and Cyproheptadine Inhibit Serotonin-Enhanced Platelet Function
There is considerable interest in defining new agents or targets for antithrombotic purposes. The 5-HT(2A) receptor is a G-protein coupled receptor (GPCR) expressed on many cell types, and a known therapeutic target for many disease states. This serotonin receptor is also known to regulate platelet...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900701/ https://ncbi.nlm.nih.gov/pubmed/24466319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087026 |
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