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A perfectly symmetric lac operator binds the lac repressor very tightly.

A completely symmetric DNA segment has been constructed that binds the lactose repressor of Escherichia coli 10-fold more tightly than does the natural lactose operator sequence. This tight-binding operator is an inverted repeat of a 15-base-pair segment from the left half of the natural operator se...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Sadler, J R, Sasmor, H, Betz, J L
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1983
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.22.6785
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