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Collagen XVI Induces Expression of MMP9 via Modulation of AP-1 Transcription Factors and Facilitates Invasion of Oral Squamous Cell Carcinoma

Collagen XVI belongs to the family of fibril-associated collagens with interrupted triple helices (FACIT). It is overexpressed during the progression of oral squamous cell carcinoma (OSCC). The present data show a strong collagen XVI-dependent induction of MMP9 and an increase in OSCC cell invasion....

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Detalhes bibliográficos
Main Authors: Bedal, Konstanze B., Grässel, Susanne, Oefner, Peter J., Reinders, Joerg, Reichert, Torsten E., Bauer, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900656/
https://ncbi.nlm.nih.gov/pubmed/24466237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086777
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