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Matrix Metalloproteinase-20 Over-Expression Is Detrimental to Enamel Development: A Mus musculus Model

BACKGROUND: Matrix metalloproteinase-20 (Mmp20) ablated mice have enamel that is thin and soft with an abnormal rod pattern that abrades from the underlying dentin. We asked if introduction of transgenes expressing Mmp20 would revert this Mmp20 null phenotype back to normal. Unexpectedly, for transg...

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Detalhes bibliográficos
Main Authors: Shin, Masashi, Hu, Yuanyuan, Tye, Coralee E., Guan, Xiaomu, Deagle, Craig C., Antone, Jerry V., Smith, Charles E., Simmer, James P., Bartlett, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900650/
https://ncbi.nlm.nih.gov/pubmed/24466234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086774
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