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Polyethyleneimine Coating Enhances the Cellular Uptake of Mesoporous Silica Nanoparticles and Allows Safe Delivery of siRNA and DNA Constructs

Surface-functionalized mesoporous silica nanoparticles (MSNP) can be used as an efficient and safe carrier for bioactive molecules. In order to make the MSNP a more efficient delivery system, we modified the surface of the particles by a functional group that enhances cellular uptake and allows nucl...

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Detalhes bibliográficos
Main Authors: Xia, Tian, Kovochich, Michael, Liong, Monty, Meng, Huan, Kabehie, Sanaz, Zink, Jeffrey I., Nel, Andre E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900639/
https://ncbi.nlm.nih.gov/pubmed/19739605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn900918w
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