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Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism

Leishmania parasites alternate between extracellular promastigote stages in the insect vector and an obligate intracellular amastigote stage that proliferates within the phagolysosomal compartment of macrophages in the mammalian host. Most enzymes involved in Leishmania central carbon metabolism are...

詳細記述

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書誌詳細
主要な著者: Saunders, Eleanor C., Ng, William W., Kloehn, Joachim, Chambers, Jennifer M., Ng, Milica, McConville, Malcolm J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900632/
https://ncbi.nlm.nih.gov/pubmed/24465208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003888
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