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Analyzing conformational dynamics of single P-glycoprotein transporters by Förster resonance energy transfer using hidden Markov models

Single-molecule Förster resonance energy (smFRET) transfer has become a powerful tool for observing conformational dynamics of biological macromolecules. Analyzing smFRET time trajectories allows to identify the state transitions occuring on reaction pathways of molecular machines. Previously, we ha...

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Autori principali: Zarrabi, Nawid, Ernst, Stefan, Verhalen, Brandy, Wilkens, Stephan, Börsch, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900600/
https://ncbi.nlm.nih.gov/pubmed/23891547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.07.026
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