Inhibition of transcription in somatic cells by microinjection of antibodies to chromosomal proteins.
The in vivo function of defined chromosomal proteins was examined by microinjecting purified antibody and antibody fragments into living fibroblasts. The involvement of histones and chromosomal high mobility group proteins HMG-1, 2, and 17 in transcription was visualized by studying the [3H]uridine...
Gespeichert in:
| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1983
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6196774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.22.6735 |
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