Detection of Novel Visible-Light Region Absorbance Peaks in the Urine after Alkalization in Patients with Alkaptonuria

BACKGROUND: Alkaptonuria, caused by a deficiency of homogentisate 1,2-dioxygenase, results in the accumulation of homogentisic acid (2,5-dihydroxyphenylacetic acid, HGA) in the urine. Alkaptonuria is suspected when the urine changes color after it is left to stand at room temperature for several hou...

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Autori principali: Tokuhara, Yasunori, Shukuya, Kenichi, Tanaka, Masami, Mouri, Mariko, Ohkawa, Ryunosuke, Fujishiro, Midori, Takahashi, Tomoo, Okubo, Shigeo, Yokota, Hiromitsu, Kurano, Makoto, Ikeda, Hitoshi, Yamaguchi, Seiji, Inagaki, Shinobu, Ishige-Wada, Mika, Usui, Hiromi, Yatomi, Yutaka, Shimosawa, Tatsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900575/
https://ncbi.nlm.nih.gov/pubmed/24466168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086606
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