Comparative Effects of Prolonged and Intermittent Stimulation of the Glucagon-Like Peptide 1 Receptor on Gastric Emptying and Glycemia

Acute administration of glucagon-like peptide 1 (GLP-1) and its agonists slows gastric emptying, which represents the major mechanism underlying their attenuation of postprandial glycemic excursions. However, this effect may diminish during prolonged use. We compared the effects of prolonged and int...

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Detalhes bibliográficos
Main Authors: Umapathysivam, Mahesh M., Lee, Michael Y., Jones, Karen L., Annink, Christopher E., Cousins, Caroline E., Trahair, Laurence G., Rayner, Chris K., Chapman, Marianne J., Nauck, Michael A., Horowitz, Michael, Deane, Adam M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Pharmacology and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900552/
https://ncbi.nlm.nih.gov/pubmed/24089511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0893
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