Fisetin Inhibits Human Melanoma Cell Invasion through Promotion of Mesenchymal to Epithelial Transition and by Targeting MAPK and NFκB Signaling Pathways

Malignant melanoma is responsible for approximately 75% of skin cancer-related deaths. BRAF plays an important role in regulating the mitogen-activated protein kinase (MAPK) signaling cascade in melanoma with activating mutations in the serine/threonine kinase BRAF occurring in 60–70% of malignant m...

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Hlavní autoři: Pal, Harish Chandra, Sharma, Samriti, Strickland, Leah Ray, Katiyar, Santosh K., Ballestas, Mary E., Athar, Mohammad, Elmets, Craig A., Afaq, Farrukh
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900533/
https://ncbi.nlm.nih.gov/pubmed/24466036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086338
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