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PEP-1-PON1 Protein Regulates Inflammatory Response in Raw 264.7 Macrophages and Ameliorates Inflammation in a TPA-Induced Animal Model

Paraoxonase 1 (PON1) is an antioxidant enzyme which plays a central role in various diseases. However, the mechanism and function of PON1 protein in inflammation are poorly understood. Since PON1 protein alone cannot be delivered into cells, we generated a cell permeable PEP-1-PON1 protein using pro...

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Detalhes bibliográficos
Main Authors: Kim, Mi Jin, Jeong, Hoon Jae, Kim, Dae Won, Sohn, Eun Jeong, Jo, Hyo Sang, Kim, Duk-Soo, Kim, Hyun Ah, Park, Eun Young, Park, Jong Hoon, Son, Ora, Han, Kyu Hyung, Park, Jinseu, Eum, Won Sik, Choi, Soo Young
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900452/
https://ncbi.nlm.nih.gov/pubmed/24465855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086034
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