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DNA sequences near the site of reciprocal recombination between a c-myc oncogene and an immunoglobulin switch region.
The chromosomal translocations found in many B-cell tumors result in the joining of a c-myc oncogene with an immunoglobulin heavy chain switch region. This finding is striking because the natural function of switch regions is to mediate DNA rearrangements important to the maturation of immune respon...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1983
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390036/ https://ncbi.nlm.nih.gov/pubmed/6316351 |
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