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Mechanisms of integration of de novo-synthesized polypeptides into membranes: signal-recognition particle is required for integration into microsomal membranes of calcium ATPase and of lens MP26 but not of cytochrome b5.

We have investigated the in vitro integration into dog pancreas microsomal membranes of three integral membrane proteins that were synthesized de novo in a wheat germ cell-free translation system: calcium ATPase of rabbit sarcoplasmic reticulum, MP26 of bovine lens fiber plasma membrane, and rat liv...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Anderson, D J, Mostov, K E, Blobel, G
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1983
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390032/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6227918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.23.7249
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