Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis

Wnt/β-catenin signaling is a central regulator of adult stem cells. Variable sensitivity of Wnt reporter transgenes, β-catenin’s dual roles in adhesion and signaling, and hair follicle degradation and inflammation resulting from broad deletion of epithelial β-catenin, have precluded clear understand...

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Main Authors: Choi, Yeon Sook, Zhang, Yuhang, Xu, Mingang, Yang, Yongguang, Ito, Mayumi, Peng, Tien, Cui, Zheng, Nagy, Andras, Hadjantonakis, Anna-Katerina, Lang, Richard A., Cotsarelis, George, Andl, Thomas, Morrisey, Edward E., Millar, Sarah E.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900235/
https://ncbi.nlm.nih.gov/pubmed/24315444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.10.003
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