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Modification of glycogen synthase activity in isolated rat hepatocytes by tumor-promoting phorbol esters: evidence for differential regulation of glycogen synthase and phosphorylase.

Glycogen synthase (UDPglucose:glycogen 4-alpha-D-glucosyltransferase, EC 2.4.1.11), in isolated rat hepatocytes, has been identified as a novel intracellular target for tumor-promoting phorbol esters such as phorbol 12-tetradecanoate 13-acetate (TPA). Exposure of hepatocytes to TPA resulted in a 50%...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Roach, P J, Goldman, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390015/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6417664/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.23.7170
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