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Regulation of Fibroblast Growth Factor-2 Expression and Cell Cycle Progression by an Endogenous Antisense RNA

Basic fibroblast growth factor (FGF2) is a potent wide-spectrum mitogen whose overexpression is associated with immortalization and unregulated cell proliferation in many tumors. The FGF2 gene locus is bi-directionally transcribed to produce FGF2 mRNA from the “sense” strand and a cis-antisense RNA...

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Autors principals: Baguma-Nibasheka, Mark, MacFarlane, Leigh Ann, Murphy, Paul R.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899992/
https://ncbi.nlm.nih.gov/pubmed/24704982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes3030505
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