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Altered Ca(2+) Homeostasis and Endoplasmic Reticulum Stress in Myotonic Dystrophy Type 1 Muscle Cells
The pathogenesis of Myotonic Dystrophy type 1 (DM1) is linked to unstable CTG repeats in the DMPK gene which induce the mis-splicing to fetal/neonatal isoforms of many transcripts, including those involved in cellular Ca(2+) homeostasis. Here we monitored the splicing of three genes encoding for Ca(...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899969/ https://ncbi.nlm.nih.gov/pubmed/24705164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes4020275 |
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